2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N4213
    Anemarrhenasaponin I 163047-21-0 99.43%
    Anemarrhenasaponin I, a traditional Chinese medicine, shows remarkable inhibiting effect on platelet aggregation.
    Anemarrhenasaponin I
  • HY-N4267
    Yangambin 13060-14-5 98.27%
    Yangambin, a furofuran lignan, is already isolated from plants such as member of the Annonaceae family, including species of the genus Rollinia: R. pickeli, R. exalbidaand R. mucosa, as well from the Magnolia biondii. Yangambin, a selective PAF receptor antagonist, inhibits Ca2+ influx through voltage-gated Ca2+ channels, leading to the reduction in [Ca2+]i in vascular smooth muscle cells and consequent peripheral vasodilation. Yangambin exhibits the antiallergic activity against β-hexosaminidase release with an IC50 of 33.8 μM and for anti-inflammatory activity with an IC50 of 37.4 μM.
    Yangambin
  • HY-N5006
    Guanfu base G 78969-72-9 99.91%
    Guanfu base G is an antiarrhythmic alkaloid isolated from Aconitum coreanum. Guanfu base G inhibits HERG channel current with an IC50 of 17.9 μM.
    Guanfu base G
  • HY-N5014
    Liensinine perchlorate 2385-63-9 99.67%
    Liensinine Perchlorate is a constituent of?Nelumbo nucifera?Gaertn, with ani-hypertension and anti-cancer activities. Liensinine Perchlorate induces?colorectal cancer (CRC) cell apoptosis.
    Liensinine perchlorate
  • HY-N5037
    Ilexoside D 109008-27-7 99.42%
    Ilexoside D is isolated from the roots of Ilex pubescens Hook. et Arn. Ilexoside D has the anti-tissue factor activity as well as the antithrombotic activity.
    Ilexoside D
  • HY-N5057
    Przewalskinic acid A 136112-75-9 98.64%
    Przewalskinic acid A is a phenolic acid found in the Salvia przewalskii Maxim herb. Phenolic acids show potent antioxidant activities and potential effects in protecting against brain and heart damage caused by ischemia reperfusion.
    Przewalskinic acid A
  • HY-N6249
    Feretoside 27530-67-2 98.69%
    Feretoside, a phenolic compound extracted from the barks of E. ulmoides, is a HSP inducer which act as cytoprotective agent.
    Feretoside
  • HY-N6574
    Marinobufogenin 470-42-8 99.0%
    Marinobufogenin is a strong inhibitor of Na+/K+ ATPase that has been identified in mammalian plasma.
    Marinobufogenin
  • HY-N6581
    Notoginsenoside T5 769932-34-5
    Notoginsenoside T5 is a dammarane 61 glycoside. Notoginsenoside T5 is isolated from the acidic deglycosylation of saponins from the roots of P. 62 notoginseng.
    Notoginsenoside T5
  • HY-N6617
    Norswertianolin 54954-12-0 99.27%
    Norswertianolin acts as a CSE activator and is isolated from G. acuta. Norswertianolin may be a potential agent for cardiovascular diseases.
    Norswertianolin
  • HY-N8049
    Urolithin M7 531512-26-2 98%
    Urolithin M7 is an orally active metabolite, which is generated through gut microbiota metabolism. Urolithin M7 inhibits oxidative stress and modulates inflammatory signaling pathways. Urolithin M7 is promising for research of gut microbiota metabolism and cardiovascular diseases.
    Urolithin M7
  • HY-N8144
    Niga-ichigoside F1 95262-48-9 99.0%
    Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis.
    Niga-ichigoside F1
  • HY-N8251
    Cyclocurcumin 153127-42-5 99.48%
    Cyclocurcumin is a potent p38α inhibitor. Cyclocurcumin shows antirheumatic, antivasoconstrictive and antioxidant activities.
    Cyclocurcumin
  • HY-N8630
    Oleacein 149183-75-5
    Oleacein (Compound 9) is an ACE inhibitor that can be isolated from J. grandiflorum. Oleacein is orally active and can be used in the study of metabolic and cardiovascular diseases.
    Oleacein
  • HY-N9347
    Stepharine 2810-21-1 98.0%
    Stepharine, an natural alkaloid, directly interactes with TLR4 and binds to the TLR4/MD2 complex (TLR4 inhibitor). Stepharine possesses anti-aging, anti-viral and anti-hypertensive effects.
    Stepharine
  • HY-N9351
    Cleistanthin B 30021-77-3 98.19%
    Cleistanthin B (Diphyllin O-glucoside) is an orally active arylnaphthalene lignan lactone glycoside. Cleistanthin B exhibits anti-SARS-CoV-2 effects in Vero cells, with EC50 of 6.51 µM. Cleistanthin B also exhibits antitumor, diuretic and antihypertensive effects in vivo.
    Cleistanthin B
  • HY-N9372
    Crocetin β-D-glucopyranoside 58050-17-2 98.59%
    Crocetin β-D-glucopyranoside is an active part of saffron pigments extracted from patent CN 105935363 A.
    Crocetin β-D-glucopyranoside
  • HY-NP203
    High density lipoprotein (human) ≥98%
    High density lipoprotein (HDL) (human) is a functional lipoprotein that binds to receptors such as scavenger receptor B1 (SR-B1), ABCA1 and ABCG1. High density lipoprotein (human) clears excess cholesterol from peripheral tissues through reverse cholesterol transport (RCT) and transports it to the liver for metabolism, while activating endothelial nitric oxide synthase (eNOS) to produce nitric oxide (NO), exerting antioxidant, anti-inflammatory, and vascular endothelial protective activities. High density lipoprotein (human) is promising for research of cardiovascular diseases, such as atherosclerosis.
    High density lipoprotein (human)
  • HY-NP204
    Human Serum Albumin-AF750
    Human Serum Albumin-AF750 is a biochemical reagent conjugated to fluorescein AF750 (Ex=752 nM; Em=780 nm). Human Serum Albumin-AF750 can be used to label or detect specific antigens, molecules or cellular structures.
    Human Serum Albumin-AF750
  • HY-P0204
    Endothelin-3, human, mouse, rabbit, rat 117399-93-6 98%
    Endothelin-3, human, mouse, rabbit, rat is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
    Endothelin-3, human, mouse, rabbit, rat
Cat. No. Product Name / Synonyms Application Reactivity