2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-152106A
    (+)-BAY-7081 99.21%
    (+)-BAY-7081 is an optical isomer of BAY-7081 (HY-152106). BAY-7081 is a potent, selective, orally active and soluble cyanopyridone-based PDE9A inhibitor with an IC50 of 15 nM.
    (+)-BAY-7081
  • HY-152106B
    (±)-BAY-7081 99.06%
    (±)-BAY-7081 is a racemate of BAY-7081 (HY-152106). BAY-7081 is a potent, selective, orally active and soluble cyanopyridone-based PDE9A inhibitor with an IC50 of 15 nM.
    (±)-BAY-7081
  • HY-15284S1
    Prasugrel-d3 1127253-02-4 ≥98.0%
    Prasugrel-d3 is the deuterium labeled Prasugrel. Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation.
    Prasugrel-d3
  • HY-17447AG
    Tranylcypromine hydrochloride (GMP) 1986-47-6 98%
    Tranylcypromine (SKF 385) hydrochloride (GMP) is Tranylcypromine hydrochloride (HY-17447A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Tranylcypromine hydrochloride is a potent monoamine oxidase (MAO) inhibitor.
    Tranylcypromine hydrochloride (GMP)
  • HY-18204S2
    Valsartan-d8 1089736-72-0 ≥99.0%
    Valsartan-d8 is the deuterium labeled Valsartan. Valsartan (CGP 48933) is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research.
    Valsartan-d8
  • HY-B0231BS
    Enalaprilat-d5 sodium 1356922-29-6 ≥98.0%
    Enalaprilat-d5 (sodium) is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor.
    Enalaprilat-d5 sodium
  • HY-B0471S1
    Phenylephrine-2,4,6-d3 hydrochloride 1276197-50-2 99.90%
    Phenylephrine-2,4,6-d3 (hydrochloride) is the deuterium labeled Phenylephrine hydrochloride. (R)-(-)-Phenylephrine hydrochloride is a selective α1-adrenoceptor agonist with pKis of 5.86, 4.87 and 4.70 for α1D, α1B and α1A receptors respectively.
    Phenylephrine-2,4,6-d3 hydrochloride
  • HY-B0715S2
    Pentoxifylline-d5 1185995-18-9 99.86%
    Pentoxifylline-d5 is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation.
    Pentoxifylline-d5
  • HY-N0437S2
    Progesterone-13C3 327048-87-3 99.60%
    Progesterone-13C3 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
    Progesterone-13C3
  • HY-N0437S3
    Progesterone-13C2 82938-07-6 99.7%
    Progesterone-13C2 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
    Progesterone-13C2
  • HY-N0666S6
    L-Aspartic acid-1,4-13C2 101247-29-4 ≥99.0%
    L-Aspartic acid-1,4-13C2 is the 13C-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.
    L-Aspartic acid-1,4-13C2
  • HY-N0684S3
    Vitamin K1-13C6 ≥99.0%
    Vitamin K1-13C6 is the 13C-labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
    Vitamin K1-13C6
  • HY-N6685S1
    3-Acetyldeoxynivalenol-13C17 1217476-81-7 ≥99.0%
    3-Acetyldeoxynivalenol-13C17 is the 13C labeled 3-Acetyldeoxynivalenol (HY-N6685). 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative, is a blood-brain barrier (BBB) permeable mycotoxin.
    3-Acetyldeoxynivalenol-13C17
  • HY-P10948A
    CS-VIP 8 TFA
    CS-VIP 8 TFA is a selective allosteric WDR5 protein inhibitor (Ki= 0.008 μM). CS-VIP 8 TFA induces conformational changes in the MLL1 complex, leading to the dissociation of MLL1 from the complex, inhibiting MLL1 histone methyltransferase activity and regulating HOX gene expression. CS-VIP 8 TFA is promising for research of hematological diseases such as leukemia.
    CS-VIP 8 TFA
  • HY-U00344A
    Theodrenaline hydrochloride 2572-61-4
    Theodrenaline hydrochloride is a cardiac stimulant, also acts as an anti-hypotensive agent together with Cafedrine.
    Theodrenaline hydrochloride
  • HY-W008606
    Sodium citrate monobasic 18996-35-5
    Sodium citrate monobasic (Citric acid monosodium salt) is a natural preservative and food tartness enhancer. Sodium citrate monobasic induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Sodium citrate monobasic cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Sodium citrate monobasic is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries.
    Sodium citrate monobasic
  • HY-W011616
    Cardionogen 1 577696-37-8 99.21%
    Cardionogen 1 (CDNG1/vuc230) is a Wnt signaling pathway inhibitor that slows down Myc-induced liver tumorigenesis. Cardionogen 1 treatment of zebrafish embryos before gastrulation inhibits cardiomyocyte formation, whereas treatment during or after gastrulation induces cardiomyocyte formation. Cardionogen 1 has potential in research into cancer and cardiovascular disease.
    Cardionogen 1
  • HY-W042039
    Methyl homoveratrate 15964-79-1
    Methyl homoveratrate, a metabolite of RWJ-26240 in vivo, can be identified in plasma, urine and faecal extract. McN5691 (RWJ-26240) is a voltage-sensitive calcium channel blocker.
    Methyl homoveratrate
  • HY-W067572
    Stobadine 85202-17-1 ≥99.0%
    Stobadine is a potent antioxidant and prevents free radical induced alterations in ER membrane fluidity. Stobadine can be used for effective cardio- and neuroprotectants development based on antioxidant or free radical scavenging mechanisms of action.
    Stobadine
  • HY-W402064
    N-Acetyladenosine 16265-37-5 99.86%
    N-Acetyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
    N-Acetyladenosine
Cat. No. Product Name / Synonyms Application Reactivity